Azoles and its derivatives are associated with various biological activities as antifungal, antibacterial, anti-inflammatory,herbicida, anthelmintic, CNS depressant, antitumor agent, anticancer,antiparasitic, analgesic, anticonvalsant, antipyretic and antihypertensive activity. 3-arylamino-1,2,4-triazole derivative is remarkably promising in pharma industries. The book has mainly deals with1,2,4- triazol's reaction scheme, experimental part, spectral studies, biological evaluation and discuss with Result and Discussion including Spectroscopy. The book is written for students in chemistry, pharmacy, microbiology or related disciplines who are already familiar with synthesis of organic moieties and their therapeutic evaluation.